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Implications of the non-specific effect induced by Bacillus Calmette-Guerin (BCG) vaccine on vaccine recommendations
CONCLUSIONS: Despite evidence obtained from in vitro studies, and some epidemiological and clinical evidence, more robust evidence of in vivo efficacy is still needed to justify the use of BCG in clinical practice, in addition to what is recommended by the National Immunization Program for TB prevention and bladder cancer treatment.PMID:36309066 | DOI:10.1016/j.jped.2022.09.002
Source: Jornal de Pediatria - October 29, 2022 Category: Pediatrics Authors: Ekaterini Goudouris Carolina Sanchez Aranda Dirceu Sol é Source Type: research

HPV vaccination programs in LMIC: is it time to optimize schedules and recommendations?
CONCLUSION: Single-dose HPV vaccination could substantially reduce the incidence of pre-cancer and cervical cancer attributable to HPV, with reduced costs for vaccine delivery and simplified implementation, allowing more countries to introduce HPV vaccination or increase the adherence of the target population.PMID:36638833 | DOI:10.1016/j.jped.2022.11.012
Source: Jornal de Pediatria - January 13, 2023 Category: Pediatrics Authors: Luisa Lina Villa Rosana Richtmann Source Type: research